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Southern Africa's rural and impoverished communities are some of the hardest hit by the HIV and AIDS pandemic. Large numbers of vulnerable children in these AIDS-affected communities struggle to access resources and services they desperately need and are entitled to. Despite this, most children still attend school, making schools an obvious avenue through which to address the multiplicity of needs of vulnerable children. The case study presented here describes an innovative and effective programme built on the principles of a multi-sectoral approach to HIV and AIDS. …