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This quasi-experimental study explores 575 secondary technical school students' knowledge on AIDS after a short health education program in Assiut City. Students were recruited using two-stage stratified cluster sampling and completed an anonymous, self-administered questionnaire. Pre and post testing was used to identify changes in knowledge. Only 30.8% students had satisfactory knowledge on AIDS prior to the health program. Statistically significant increases in knowledge were found after program implementation (P0.001). …