This report summarizes the key discussions and recommendations emanating from the meeting, which can be used collectively as a “Call to Action” as well as a tool for regional stakeholders including national health, education, and social sector authorities and programs, regional partners, civil society, communities, parents, and young people, to intensify efforts, revise and update strategies, and scale up approaches that: 1) empower adolescent girls to prevent unplanned and unwanted pregnancies, 2) protect them from sexual violence, 3) improve their development opportunities, and 4) help them realize their right to thehighest attainable standard of health and to participate fully in public and political life.