The main objective of the study was to determine the influence of Menstrual Hygiene Management on school absenteeism of adolescent girls in 10 primary schools in Lira municipality. Our findings highlighted that; majority of the respondent’s onset of the menstruation was at 13 years of age, 60% of the participants used disposable pads. Most respondents changed their pads at least twice a day. Two fifth of the primary girls reported missing school for about 3 days during menstrual periods pointing to the lack of menstrual hygiene products. However, presence of senior women teachers was found to increase the number of girls attending school during their menstruation periods.