This Handbook is both your guide to using the Young Champions Support Pack and a key information resource on HIV prevention and treatment literacy issues for young people. The Handbook is primarily intended for use in a school setting. However, it provides a bridging point for others supporting young people at community level (especially those working with young people living with HIV). The purpose of the Handbook is to provide those involved in the Young Champions initiative with a critical reference point for the key subject areas to be covered. Young Champions is all about HIV prevention and treatment literacy for young people – whether they are HIV positive or not.