This thematic paper on schools and pre-schools promoting health and well-being for all children and adolescents was produced to support and inform discussion at the high-level conference in Paris. The school and pre-school environment offers pathways to improving health outcomes, including, but not limited to: building individuals’ capacity to access, understand and use information through improved health and social literacy (a means of empowerment); tackling stereotypes and gender inequalities; ensuring a safe, inclusive and accessible health-promoting school environment; providing access to child- and adolescent-friendly health services; facilitating the transition from education to work; ensuring teaching and school staff are supported and empowered to deliver health promoting programmes and settings; and reaching out to parents to build healthy and resilient local communities. The relationship between health and well-being and education is also captured in the Sustainable Development Goals (SDGs) related health (SDG 3, good health and well-being) and education (SDG 4, quality education).