The 2015-2020 Ethiopia HIV /AIDS prevention care and treatment Strategic plan was developed in an Investment case approach by focusing on four core elements namely, understand the problem, design the optimal program to solve the problem, deliver and sustain for impact and ending AIDS. This investment cases aims to pave the path for ending AIDS by 2030 through averting 70,000- 80,000 new HIV infections and saving about half a million lives till 2020. The targets set in this investment case are in line with the three 90’s (90-90-90) treatment targets set by UNAIDS to help end the AIDS epidemic. The HIV Investment case includes four strategic objectives to achieve the goals and targets. These are: 1. Implement high impact and targeted prevention program. 2. Intensify targeted HIV testing and counseling services. 3. Attain virtual elimination of MTCT. 4. Optimize and sustain quality care and treatment.