The strategic information framework presented in this monitoring and evaluation (M&E) plan guides and allows stakeholders in the national response to provide oversight and routine performance monitoring of the national response, defined in the National Strategic Plan. It constitutes the national monitoring tool for the generation and use of strategic information to support timely, evidence-informed decision-making processes for successful policy development, program planning and implementation. The M&E plan objectives are: To facilitate the generation and use of accurate, timely and relevant data and intelligence on results and impact of the planned and implemented national response to HIV and HIV/TB; To guide the generation of strategic information that allows for the adequate provision of oversight and corrective actions to continuously improve the national response to the epidemic; To provide strategic guidance in the further capacity development of the national M&E system and its stakeholders.