This publication outlines the priority health care needs and human rights issues for transgender people in the Asia Pacific region. Drawing upon inputs from trans individuals and organizations, medical professionals, and policymakers from throughout the region, Blueprint aims to strengthen and enhance the policy-related, clinical, and public health responses for trans people in the region. This document is the third in a series of regional transgender health guidance documents, and builds on similar publications produced in Latin America and the Caribbean. The primary audience for the Blueprint is health providers, policymakers and governments. The information within the Blueprint could also serve donors, bi- and multilateral organisations and trans and other civil society organisations.