The paper gives an account on the activities of UNICEF Myanmar supported "HIV/AIDS Prevention through the Promotion of Reproductive Health Project". The six project components described in the report are: life skills and HIV/AIDS including School-based Healthy Living and HIV/AIDS Prevention Education (SHAPE); STD care and management; UNAIDS partnership building; targeting high-risk groups and ethnic minorities; responsive and innovative activities such as working with religious groups; and monitoring and evaluation. Achievements, constraints and lessons learned in the project implementation are also recounted.