This study aimed to identify effective methods to train medical personnel to educate drug users on HIV prevention. One hundred and sixty-one participants from 13 provinces were recruited at a drug relief hospital in Beijing, China. Average age was about 35.21 years, years of drug addiction was 7, and number of drug relief treatments received in past was 5.5. Participants knowledge of HIV transmission and prevention was tested before and after the HIV awareness training. Results show that there was a statistically significant increase in knowledge on these issues after education. Attitudes and behavior were also improved post-education. The study concludes that HIV and AIDS education is crucial for drug users and those seeking rehabilitation.