This review presents the results of an assessment of the policies and practices related to prevention education in ten countries in Eastern Europe and Central Asia (EECA region). It consists of a regional overview (Chapters 1–6) and ten individual country assessments (Appendices 2–11). The aim is to provide decision makers, education authorities and experts, development partners, civil society organizations (CSOs), and other stakeholders with information for discussion about the current situation related to prevention education in order to improve its quality and to support a more systematic and coordinated strategy for scaling it up across the EECA region, and ensuring that it meets agreed quality standards. The study was conducted through a desk review of relevant laws, policies, strategies, curricula, statistical data and other research findings, together with consultations with experts from national ministries of education and their institutions.