This paper examines the relationship between education and HIV/AIDS with special reference to South Asia. The paper offers an overview of major regional trends in HIV/AIDS. It looks more closely at the links between education and HIV/AIDS as well as lessons learned. The focus here is on global experience to date, although local experience within South Asia is drawn upon where it has been documented. Finally, it considers the implications of HIV/AIDS for education and development within the region - both in relation to the attainment of EFA goals and challenges ahead.