This thematic study is about the link between health, social issues and secondary education. The study is based on country studies in six Sub Saharan Africa countries (Eritrea, Mali, Namibia, Senegal, South Africa and Tanzania) and a literature review. It looks at the role of secondary education and training in promoting health, civics and life skills among the African youth. Specifically, this study focuses on examining which schooling programs are effective in equipping young people with life skills, which programs reduce dropout and increase participation and how schools can become agents in tackling health and social issues. Peer education and youth involvement are also key areas for consideration; peer education is an outstanding feature of the study's findings. Where resources are limited, community engagement becomes even more important in addressing health and civic education issues. The study also reiterates that secondary teachers are critical change agents.