Nyanza Province has been a focus of heightened attention in Kenya since the advent of the country’s HIV epidemic. A 2001 study highlighted married adolescent girls (MAG) as a particularly vulnerable population in Nyanza due to their elevated risk for HIV infection compared to other sexually active girls elsewhere in the country.Given these realities, through the USAID-funded FRONTIERS program from 2006-2008, the Population Council designed and implemented an operations research project to expand access to HIV-prevention information and services for MAG and their partners in Nyanza Province.The objectives of this operations research study were to: 1) identify and design a set of interventions that promote the uptake of comprehensive reproductive health (RH)/family planning (FP) and HIV prevention services and information among married adolescent girls; and 2) expand access to comprehensive RH/FP and HIV prevention services and information among this population.The present study aimed to expand married adolescent girls’ access to comprehensive RH/FP and HIV information and services and to test the effects of a set of interventions designed for this purpose.