This preliminary draft of the National Strategic Plan for HIV, TB and STIs 2017-2022 (NSP) outlines the strategic framework for a multi-sector partnership to accelerate progress in reducing the morbidity (illness) and mortality (death) associated with HIV, TB and STIs. The consultative process undertaken for NSP 2017-2022 resulted in agreement on seven strategic goals: 1. Accelerate prevention to reduce new HIV, TB and STI infections; 2. Reduce morbidity and mortality by providing treatment, care and adherence support for all; 3. Reach all key and vulnerable populations with comprehensive, customised and targeted interventions; 4. Address the social and structural drivers of HIV, TB and STI infections, including human rights; 5. Promote leadership at all levels and shared accountability for a sustainable response to HIV, TB and STIs; 6. Mobilise resources to support the achievement of NSP goals and ensure a sustainable response; 7. Strengthen strategic information to drive progress towards achievement of NSP goals.