This Manual is designed to be used to guide the conduct of a 6-day Trainer of Trainers workshop for approximately 20 participants. It is primarily instructor-led but may be used for self-paced learning by persons in the early childhood field. Early Childhood Education Officers and Health Promotion Education Officers will use the material and exercises to design training workshops for early childhood educators, basic-school teachers, and caregivers in day care facilities with a view to enabling them to develop a better understanding of how to competently deal with HIV and AIDS in early childhood.